Diabetes Treatment a Rapid Review of the Current and Future Scope of Stem Cell Research

Review

doi: ten.1016/j.jsps.2013.12.012. Epub 2013 December 24.

Diabetes treatment: A rapid review of the current and future scope of stem cell research

Affiliations

• PMID: 27134533
• PMCID: PMC4834680
• DOI: 10.1016/j.jsps.2013.12.012

Free PMC commodity

Review

Diabetes treatment: A rapid review of the current and future scope of stem cell research

Sheriff Sheik Abdulazeez . Saudi Pharm J. 2015 Sep .

Free PMC article

Abstruse

Diabetes mellitus is a major health concern of the developing and developed nations across the globe. This devastating disease accounts for the 5% deaths around the world annually. The current handling methods do not address the underlying causes of the disease and have severe limitations. Stem cells are unique cells with the potential to differentiate into any blazon of specialized cells. This feature of both adult and embryonic stem cells was explored in great detail by the scientists around the world and are successful in producing insulin secreting cells. The different type of stem cells (induced pluripotent stalk cells (iPSCs), embryonic stem cells (ESCs) and adult stem cells) proves to exist strong in treating diabetes with certain limitations. This article precisely reviews the resources and progress made in the field of stem prison cell enquiry for diabetic treatment.

Keywords: Diabetes; Induced pluripotency; Stem cells; β-Cells.

Figures

Effigy 1

Self renewal and differentiation potential of the stem cells.

Figure 2

Pluripotent stalk cell forms the cells of all there germ layers.

Figure 3

Different types of stem cell resources with a potential to exist developed into insulin secreting cells.

Like articles

• Stalk Jail cell Therapy for Diabetes Mellitus: Contempo Progress and Hurdles.

  Saleem One thousand, Sabir Due south, Akhtar MF, Zahid S, Niazi SG, Naeem M, Saleem U, Saleem A. Saleem Grand, et al. Crit Rev Eukaryot Gene Expr. 2019;29(5):471-482. doi: 10.1615/CritRevEukaryotGeneExpr.2019025723. Crit Rev Eukaryot Gene Expr. 2019. PMID: 32422003 Review.

• Stem Cell-Based Therapies: A New Ray of Promise for Diabetic Patients.

  Khan J, Alexander A, Agrawal M, Ajazuddin, Dubey SK, Siddique South, Saraf Southward, Saraf Southward. Khan J, et al. Curr Stem Cell Res Ther. 2019;14(2):146-151. doi: 10.2174/1574888X13666181002154110. Curr Stem Prison cell Res Ther. 2019. PMID: 30280677 Review.

• Differentiation and transplantation of functional pancreatic beta cells generated from induced pluripotent stalk cells derived from a type 1 diabetes mouse model.

  Jeon Yard, Lim H, Kim JH, Thuan NV, Park SH, Lim YM, Choi HY, Lee ER, Kim JH, Lee MS, Cho SG. Jeon G, et al. Stem Cells Dev. 2012 Sep twenty;21(14):2642-55. doi: 10.1089/scd.2011.0665. Epub 2012 Jun one. Stalk Cells Dev. 2012. PMID: 22512788 Free PMC article.

• Advances in the Generation of Functional β-cells from Induced Pluripotent Stalk Cells As a Cure for Diabetes Mellitus.

  Kalra 1000, Chandrabose ST, Ramasamy TS, Kasim NHBA. Kalra K, et al. Curr Drug Targets. 2018;xix(13):1463-1477. doi: ten.2174/1389450119666180605112917. Curr Drug Targets. 2018. PMID: 29874998 Review.

• Transcriptomic analysis of pluripotent stem cells: insights into health and disease.

  Yeo JC, Ng HH. Yeo JC, et al. Genome Med. 2011 October 27;3(10):68. doi: 10.1186/gm284. Genome Med. 2011. PMID: 22035782 Free PMC commodity.

Cited by 7 articles

• Combination treatment of autologous bone marrow stalk cell transplantation and hyperbaric oxygen therapy for type 2 diabetes mellitus: A randomized controlled trial.

  Estrada EJ, Decima JL, Bortman G, Roberti J, Romero EB, Samaja G, Saavedra AR, Martínez 1000, Gutiérrez S. Estrada EJ, et al. Cell Transplant. 2019 Dec;28(12):1632-1640. doi: 10.1177/0963689719883813. Epub 2019 October thirty. Jail cell Transplant. 2019. PMID: 31665912 Gratis PMC commodity. Clinical Trial.

• Applications of stem cells and bioprinting for potential treatment of diabetes.

  Kumar SA, Delgado Yard, Mendez VE, Joddar B. Kumar SA, et al. World J Stem Cells. 2019 Jan 26;eleven(1):xiii-32. doi: x.4252/wjsc.v11.i1.13. World J Stem Cells. 2019. PMID: 30705712 Free PMC article. Review.

• Current Status of Stem Cell Treatment for Type I Diabetes Mellitus.

  Kakkar A, Sorout A, Tiwari M, Shrivastava P, Meena P, Saraswat SK, Srivastava Due south, Datt R, Pandey S. Kakkar A, et al. Tissue Eng Regen Med. 2018 Aug 2;xv(half-dozen):699-709. doi: 10.1007/s13770-018-0143-9. eCollection 2018 December. Tissue Eng Regen Med. 2018. PMID: 30603589 Costless PMC article. Review.

• Addressing Stem Cell Therapeutic Approaches in Pathobiology of Diabetes and Its Complications.

  Peng BY, Dubey NK, Mishra VK, Tsai FC, Dubey R, Deng WP, Wei HJ. Peng Past, et al. J Diabetes Res. 2018 Jun 25;2018:7806435. doi: ten.1155/2018/7806435. eCollection 2018. J Diabetes Res. 2018. PMID: 30046616 Free PMC article. Review.

• miR‑433 protects pancreatic β prison cell growth in high‑glucose weather.

  Wang 1000. Wang M. Mol Med Rep. 2017 Sep;sixteen(3):2604-2610. doi: ten.3892/mmr.2017.6925. Epub 2017 Jul v. Mol Med Rep. 2017. PMID: 28713945 Complimentary PMC commodity.

References

1. 1. Adler R. Curing blindness with stem cells: promise, reality, and challenges. Adv. Exp. Med. Biol. 2008;613:3–20. - PubMed
2. 1. Alipio Z., Liao W., Roemer E.J., Waner M., Fink L.M., Ward D.C., Ma Y. Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stalk (iPS)-derived pancreatic β-like cells. Proc. Natl. Acad. Sci. USA. 2010;107:13426–13431. - PMC - PubMed
3. 1. Assady Due south., Maor G., Amit K., Itskovitz-Eldor J., Skorecki K.50., Tzukerman M. Insulin production by human embryonic stalk cells. Diabetes. 2001;50:1691–1697. - PubMed
4. 1. Atkinson Thousand.A., Eisenbarth K.S. Blazon I diabetes: new perspectives on illness pathogenesis and treatment. Lancet. 2001;358:221–229. - PubMed
5. 1. Ber I., Shternhall K., Perl South., Ohanuna Z., Goldberg I., Barshack I., Benvenisti-Zarum L., Meivar-Levy I., Ferber Due south. Functional, persistent, and extended liver to pancreas transdifferentiation. J. Biol. Chem. 2003;278:31950–31957. - PubMed

Publication types

LinkOut - more than resource

• Full Text Sources

  • Elsevier Science
  • Europe PubMed Central
  • PubMed Central

• Other Literature Sources

  • scite Smart Citations

briscoebetimesely.blogspot.com

Source: https://pubmed.ncbi.nlm.nih.gov/27134533/

Share this post